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Job Description Vertex is seeking a Senior Principal Research Scientist, Medicinal Chemistry to provide scientific leadership in the design and optimization of small-molecule therapeutics across discovery programs. This role will play a critical part in advancing high-quality dr
Job Description The CMC Statistics Director (Scientific Fellow) provides strategic and technical leadership for the application of statistical sciences across the product lifecycle, including process development, analytical development, manufacturing, process validation, continu
Job Description Vertex is seeking a Director, Medicinal Chemistry to provide people management and strategic leadership for small-molecule discovery programs and to help advance compounds from early discovery through candidate selection. This role is responsible for defining and
Job Description Vertex is seeking an Associate Director of Supply Chain to lead the development of upstream supply strategy for the Pain portfolio and support the Program Lead on end-to-end strategic initiatives. This role is ideal for a strategic, collaborative leader who thriv
Job Description The Product Development Engineering Scientist focuses on combination product development, with a particular focus on drug delivery systems. The Product Development Engineering Scientist will work closely with Research and Development, Device Quality Control, Devi
Job Description The Global Patient Safety Individual Case Safety Report (ICSR) Manager is responsible for performing Individual Case Safety Report (ICSR) processing activities, including case book-in, triage, case entry (structured field data-entry, event coding, narrative writi
Job Description For this Director-level role, we are seeking a scientific and technical expert to lead our agentic AI co-scientist initiative across our scientific organization. This individual will serve as the scientific lead on the project, defining and influencing the strate
Job Description The Research Scientist, Exploratory Biology will be responsible for identifying new disease opportunities that align with Vertex research strategy, designing and executing focused research studies to advance understanding of disease biology and target mechanisms,
Job Description Vertex is seeking a scientific leader to accelerate the application of AI and agentic systems across drug discovery. Working at the intersection of Computational Drug Design, project teams, Data & Methods, and Digital Technology & Engineering, this individual wil
Job Description The Associate Director, GxP Operations Support Manufacturing Systems will provide strategic leadership for the design, delivery, administration, and continuous improvement of the site Manufacturing Execution Systems (MES) and manufacturing control system platform
Job Description Vertex is seeking an accomplished Senior Principal Scientist with proven record of developing, testing and deploying scientific computational methods and agentic AI systems for drug discovery. In this role, you will work across modalities with emphasis on small m
Job Description The International PV Senior Specialist is responsible for supporting build-out and management of the GPS International PV structure. The International PV Senior Specialist works with a degree of independence and supports troubleshooting problems and improving int
Job Description The Audit & Compliance Manager manages and coordinates audit, inspection, and compliance activities across Data, Technology & Engineering (DTE) and business functions. This role serves as the primary liaison between operational teams and auditors, ensuring timely
Job Description We are seeking a Computational Genomics Research Scientist to support the development of transformative cell and gene therapies across Vertex's research portfolio. This Boston-based position is part of the global Data and Computational Sciences organization and w
Job Description We are seeking a Senior Research Scientist in Computational Genomics to join Vertex's Data and Computational Sciences organization at our San Diego research site. In this role, you will work at the intersection of human genetics, genomics, and modern computationa
Job Description The Director, Marketing Operations, Promotional Materials Management will lead Vertex’s centralized promotional materials operations function across all U.S. products and businesses. This role is responsible for the end-to-end operational management of promotiona
Job Description The Senior Director, Immunology will oversee multiple research programs and initiatives that support the research and development of the Vertex portfolio, and collaborate closely with manufacturing, process and analytical development colleagues to support the dev
Job Description Reporting to the Head of Market Access, the Market Access Senior Manager will support different aspects of the national pricing and reimbursement process for Sickle Cell Disease (SCD) , Transfusion-Dependent Thalassemia (TDT), Cystic Fibrosis and all new therapeu
Job Description We are seeking a highly motivated and experienced computational chemist to join our Computational Drug Design group in Boston. This individual will be responsible for contributing to both hit/lead identification and optimization programs using a broad range of co
Job Description The Executive Director, Finance NECAD (Norther Europe, Canada, Australia & Distributor markets) and INPP (International New Product Planning) will lead finance strategy, decision support, and performance management for both the NECAD region and International New